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Original Article
Effect of Position Change on TcPO2 in the Newborns.
Young Pyo Chang, Yong Joon Shin, Myoung Jae Choey, Beyong Il Kim, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1990;33(4):448-455.   Published online April 30, 1990
To determine the optimal position for the neonatal intensive care, transcutaneous oxygen tension (TCPO2) was monitored in 20 healthy preterm infants and 20 healthy term infants using the Radiometer Tc Oxgen Monitor in both supine and prone position. Also, transcutaneous oxygen tension (TcPO2) was monitored with tilting change in each position. When the infants were prone, TcPO2 rose by a mean of 7.36 mmHg...
A Clinical study on the Neonatal Exchange Transfusion.
S Y Song, W H Kwon, C H Han, H L Jeong, S Y Kim, Y D Kwon
Clin Exp Pediatr. 1990;33(2):162-169.   Published online February 28, 1990
A clinical observation was performed on patients with neonatal hyperbilirubinemia who were treated by exchange transfusion, and following results were obtained. Exchange transfusion was performed in 31 cases (8% of 383 csases admitted due to neonatal hyperbilirubinemia during the observation period). There was no sex predominance (male 16, female 15). Most common type of delivery was normal varginal delivery (22 cases, 71%). Birth weight of 17...
Role of aldosterone on the minimal change nephrotic syndrome in children.
Soon Wha Kim, Myung Ik Lee, Don Hee Ahn
Clin Exp Pediatr. 1989;32(11):1526-1532.   Published online November 30, 1989
We studied 11 cases of minimal change nephrotic syndrome randomly selected among 16 cases of minimal change nephrotic syndrome who were proved by kidney biopsy at department of pediatrics, National Medical Center during the period of January 1985 through December 1987. These patients were studied serially at 3 different stages in their clinical course. These were stages of edema formation, diuresis and remission, respectively. The...
Selectivity Index of Proteinuria in Childhood Minimal Change Nephrotic Syndrome.
Cheol Ho Lee, Young Seo Park, Kwang Wook Ko
Clin Exp Pediatr. 1989;32(10):1384-1390.   Published online October 31, 1989
The selectivity indices (S.I.) of proteinuria in 120 biopsy proven minimal change nephrotic syn- drome (MCNS) children who were admitted to Seoul National University Childern’s Hospital from January 1976 to June 1988 and followed up for more than 1 year from onset of disease, were analyzed in relation to clinical findings, histopathologic features and steroid responsiveness. The results were as follows: 1) The mean age at...
Serum IgE Level in Patients with Minimal Change Nephrotic Syndrome.
Sung Oh Kim, Hee Jung Ahn, Seong Ho Kim, Woo Gill Lee
Clin Exp Pediatr. 1989;32(6):789-796.   Published online June 30, 1989
It has been reported that many patients with minimal change nephrotic syndrome(MCNS) have high serum IgE level, but its significance has not been disclosed yet. In this study, serum levels of IgE were evaluated in different stages of the disease with or without treatment in 26 MCNS(proven by renal biopsy) patients admitted to the Department of Pediatrics Hanyang University Hospital from January, 1980 to...
Acid-Base and Electrolyte Change Before and After Exchange Transfusion with ACD-B Blood in Hyperbilirubinemia of Newborn.
Ki Hong Park, Chong Woo Bae, Yong Mook Choi, Chang Ill Ahn, Jung Kook Lee
Clin Exp Pediatr. 1989;32(3):311-320.   Published online March 31, 1989
Exchange transfusion is being used widely to correct anemia and control existing hyperbilirubinemia for the prevention of kernicterus in newborn. But the blood used for exchange transfusion is stored blood containing anticoagulants and other substances. So many metabolic changes can be developed after exchange transfusion. This study was undertaken to evaluate the acid-base and electrolyte change after exchange transfusion using the ACD-B blood. In...
A Case of Congenital Nephrotic Syndrome.
Choong Sun Kang, Chang Hee Hwang, Pyung Kil Kim, Hyeon Joo Jeong, In Joon Choi, Jung Hye Choi
Clin Exp Pediatr. 1988;31(5):627-634.   Published online May 31, 1988
Congenital nephrotic syndrome is an uncommon disorder, which is caused by a heterogenous group of renal diseases with variable etiology and natural history. It may be inherited, sporadic, acquird or a part of a general malformation syndrome. This disorder has no single or pathological feature for pathognomonic finding, and there is no ultimate curative treatment except renal transplantation. We experienced a case of congenital...
A Study on Minimal Change Nephrotic Syndrome in Children.
Yong Choi, Hong Jin Lee, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
Clin Exp Pediatr. 1988;31(2):220-226.   Published online February 28, 1988
To assess the clinical significance of histopathologic variants of minimal change nephrotic syn- drome (MCNS) by light microscopic findings, 148 biopsy proven MCNS patients, who were admitted to Seoul National University Hospital between the period from January 1976 to December 1986, were analyzed according to clinical findings, steroid responsiveness, and follow up status in relation to the pathologic variants. The followings are summary and conclusion. 1) Significantly...
Developmental Changes of Auditory Brainstem Responses in Children.
Jeong Sik Min, Yeong Ho Ra, Chong Woo Bae, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1987;30(12):1387-1400.   Published online December 31, 1987
Auditory Brainstem Response(ABR) has been found to be useful for evaluating objective assessment of hearing thresholds, maturation of the brainstem and neurological disorders in the brainstem. Therefore it is essential to define normal ranges and accurate changes in the wave form of the ABR in children. This study was undertaken with the analysis of 243 ABR in children with normal otological, developmental, neurological...
A Retrospective Study on the Effect of Cyclophosphamide in Children with Minmal Change Nephrotic Syndrome.
Il Soo Ha, Kwang Wook Ko, Yong Il Kim
Clin Exp Pediatr. 1987;30(2):158-174.   Published online February 28, 1987
Thirty one children associated with biopsy-proven minimal change nephrotic syndrome with frequent relapse, were placed on cyclophosphamide, and its effect was analyzed. Cyclophosphamide was given with the dosage of 2.46±0.42 mg/kg/day for 58±7 days along with the alternate day corticosteroid. Sixty three percent of the patients showed complete remission and twenty seven percent of the patients resulted in partial remission after the treatment. Those...
Experimental Diphtheritic Myocarditis with Special Reference to Ultrastructural Changes.
Hyo Seop Ahn
Clin Exp Pediatr. 1986;29(12):1295-1308.   Published online December 31, 1986
Myocardiopathy following diphtheria infection is one of the most serious and fatal complications, but its nature of the lesion remained in controversy, and even ultrastructural understanding on the direct effect of diphtheria toxin has not been clarified. The purpose of this experiment is to illustrate the full morphological spectrum of subclinical or EKG free diphtheritic myocardial injuries by administration of...
Developmental Changes of Auditory Brainstem Responses in Infancy.
Soo Kon Chai, Yeong Ho Ra, Sa Joon Chung, Chang Il Ahn
Clin Exp Pediatr. 1986;29(10):1114-1129.   Published online October 31, 1986
Auditory Brainstem Response (ABR) has been found to be useful evaluating objective assessment of hearing thresholds, maturation of the brainstem and neurological disorders in the brainstem. Therefore it is essential to define normal ranges and accurate changes in the wave form of the ABR. This study was undertaken with the analysis of 137 ABR in premature infants in a newborn...
Clinical Studies on Neonatal Jaundice and Exchange Transfusion.
Byoung Hun Kim, Soo Yup Lee, Jeh Hoon Shin, Kyu Hwan Lee, Soo Jee Moon, Chong Moo Park
Clin Exp Pediatr. 1986;29(5):535-542.   Published online May 31, 1986
Jaundice occurs rather frequently in neonatal period, and yet the irreversible complication, kernicterus, may occur in severe cases with pathologic jaundice, from which the patients are at high risk for mental retardation, cerebral palsy, and even death. To prevent this complication, aggressive measures have been used for the neonatal janudice, such as phototherapy and exchange transfusion. Exchange transfusion has been...
A Study of 60 Cases of Exchange Transfusion.
Si Bok Jo, Im Ju Kang, Jae Keun Yoon, Hae Jin Suh
Clin Exp Pediatr. 1984;27(11):1055-1062.   Published online November 30, 1984
Clinical study was made of 60 cases who were received blood exchange transfusion at Taegu Fatima Hospital from January, 1978 to December, 1980 with the following results. 1) Among 1,387 cases of neonatal hyperbilirubinemia, the exchange transfusion was performed on 60 ases(4.3%). 2) The most predominant delivery type was normal vertex delivery at local clinics. 3) The most common cause of performed exchange transfusion was unknown...
Case Report
Rifampin Induced Nonresponsiveness to Steroid Therapy in Children with Minimal Change Nephrotic Syndrome .
Hae Il Cheong, Sang Bok Suk, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1984;27(5):506-510.   Published online May 31, 1984
We experienced three children with the biopsy proven minimal change nephrotic syndrome who had failed to respond to prednisolone, 60 mg/m2/d for 4 to 9 weeks due to concomittent administration of rifampin. Because rifampin is a known enzyme inducer of the liver like phenobarbital and dilantin which can increase the clearance of the other drugs such as steroid etc., rifampin were...
Two Cases of Anomalous Origin of the Right Pulmonary artery from the Ascending Aorta.
Kyu Gap Hwang, Gu Soo Kim, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1984;27(5):501-505.   Published online May 31, 1984
Anomalous origin of one pulmonary artery from the ascending aorta is a rare congenital malformation. It happens as the result of abnormal development of the 6th aortic arch. Anomalous origin of right pulmnary artery is more frequent than left. It is frequently associated with P.D.A., V.S.D. and T.O.F. In this malformation, congestive heart failure develops in early life and once the...
Original Article
The Response of Leukocytes in the Peripheral Blood Following Exchange Transfusion in the Newborn.
Young Mo Sohn, Yu Young Chang, Young Ho Kim, Kir Young Kim
Clin Exp Pediatr. 1983;26(11):1049-1054.   Published online November 30, 1983
We have studied the hemoglobin level and. leukocyte count of 23 fullterm and 1 premature jaundiced babies soon after exchange transfusion and daily thereafter until 7 days. The resixlts are: 1) One exchange transfusion was enough in 16 patients but 8 were required more than 2times of exchange transfusion. The maximum is 6 times. 2) The postnatal age was...
Clinical and Follow up Study of 52 cases of Blood Exchange Transfusion for Neonatal Hyperbilirubinemia.
Hong In Eum, Jae Gae Rheu, Sang Cheol Lee, Jung Hee Lee
Clin Exp Pediatr. 1983;26(10):996-1003.   Published online October 31, 1983
The study was made of 52 cases of neonatal hyperbilirubinemia receiving blood exchange transfusion at St. Benedict Hospital from January 1977 to June 1981 with the following results; 1) 34.6% of total exchanged patients were born at St. Benedict hospital. Remains were born at outside. 2) 27 patients(51.9%) returned for follow up, 21 patients(40.4%) not returned for follow up 4 patients (7.7%) had died. 3) The...
A Study on the Renal Function in Neonates and Children.
In Soo Choi, Young Sook Kim, Soo Chul Cho, Jung Soo Kim, Kyung Woo Cho
Clin Exp Pediatr. 1983;26(8):744-750.   Published online August 31, 1983
A study on the renal function and its changes by aging in neonates and children has been done, and the result obtained were as follow. 1) Urinary output, creatinine and electrolyte excretion in neonates (age: 12 〜 24 hrs) were significantly lower than children over 1 〜2 yrs, and urine concentrating ability may not yet t>e matured. 2) Urinary output, creatinine and electrolyte excretion in children...
Lipoprotein Profiles in Minimal Change Nephrotic Syndrome.
Yong Choi, Heui Jeen Kim, Hae Il Cheong, Jeong Kee Seo, Kwang Wook Ko
Clin Exp Pediatr. 1983;26(3):237-246.   Published online March 31, 1983
Data obtained from 59 hospitalized patients with minimal change nephrotic syndrome which was confirmed by kidney biopsy, were analyzed for serum albumin, serum lipids, 24hr urine protein, creatinine clearanee, HDL-eholesterol. In 38 of the patients, lipoproteins were analyzed. The following results were obained 1. Serum phospolipid (PL) was increased whenever serum total cholesterol (TC) was increased but to a lesser degree. The ratio of TC/PL were...
A Clinical Study on Children with Acute Glomerulonephritis.
Jeong Gwon Lee, Dong Jin Lee, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1983;26(1):48-56.   Published online January 31, 1983
A clinical observation has been made on 104 children with acute glomerulonephritis who were admitted to pediatric Dept, of Kyung-Pook University hospital during 4 1/2 year period, from August 1977 to December 1981. Male to female ratio was 1.5 ： 1 and peak incidence was noticed on cold months from November to January when URI was most prevalent. Cases were evenly distributed...
Clinical Observation in Epidemic Encephalitis.
Hye Keun Kim, Young Jong Woo, Tai Ju Whang, Hyung Suk Byun, Chull Shon
Clin Exp Pediatr. 1983;26(1):26-33.   Published online January 31, 1983
A clinical observation and statistical management on 592 cases of epidemic encephalitis admitted to the department of pediatrics, Chonnam University Hospital with 10 years duration from 1971 to 1980 were carried out. The following results are obtained: 1) No periodical change was observed in annual incidence during these 10 years. 2) The annual incidence was higher when the annual average temperature was higher. Most of the...
The Study on 182 Cases of Exchange Transfusion.
Gie Hwa Yoon, Ock Seung Jeong, So Won Ahn, Yung Seok Jeon
Clin Exp Pediatr. 1982;25(12):1243-1251.   Published online December 31, 1982
Clinical and statistical observations were performed on 182 cases who were received blood exchange transfusions at II Sin Women’s Hospital from January, 1978. to December, 1980. The results are as follows: 1. Among 1534 case of neonatal jaundice, the exchange transfusion was performed on 182 cases (8.4%). 2. The most predominant etiologies of exchange transfusion were ABO incompatibility (37.4 %) and prematurity(20.9%). 3. The total incidence of repeated exchange transfusion...
Case Report
Hyperviscosity Syndrome in Newborn.
Yong Soon Kim, Sook Hee Lee, Ja Hoon Koo, Doo Hong Ahn
Clin Exp Pediatr. 1982;25(6):622-627.   Published online June 30, 1982
We experienced Hyperviscosity syndrome in 5 newborn infants during 6 months period from August 1980 to January 1981. Diagnosis was made on the basis of characteristic clinical symp-toms along with polythemia. The following results were obtained. Sex in 5 affected infants showed male in 2 and female in 3. And gestational age showed preterm in 3 and full term in...
Original Article
A Follow-up Study of Newborns who had Exchange Blood Transfusion for Hyperbilirubinemia.
Young Soo Yoon, Seung Joon Park, Ki Bok Kim
Clin Exp Pediatr. 1981;24(9):826-836.   Published online September 15, 1981
A follow up study was made of 59 cases of neonatal hyperbilirubinemia receving blood exchange transfusion at Kwangju Christian Hospital from early 1976 to early 1979, with the following results. 1. 42patients(71.2%) returned for followup: 12 patients(20.3%) did not return; and 5 patients(8.5%) had died. 2. Of those returning, developmental status was studied by D.D.S.T. 38 patients(90.5%) had normal development...
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